Immune response stimulating composition comprising nanoparticles based on a methyl vinyl ether-maleic acid copolymer

The composition for stimulating an immune response in a subject comprises methyl vinyl ether and maleic anhydride copolymer-based nanoparticles. Said nanoparticles may further contain an allergen or an antigen and/or an immunostimulating agent, which may be contained inside said nanoparticles and/or...

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Hauptverfasser: DE LA RASILLA CARLOS GAMAZO, PUGA MARTA FERRER, MARTINEZ SARA GÓMEZ, IRACHE GARRETA JUAN MANUEL, LARRUGA MARIA LUISA SANZ, SALMAN HESHAM H. A, ABERASTURI BEATRIZ SAN ROMÁN, REP{DOT OVER (A)}RAZ JAVIER OCHOA
Format: Patent
Sprache:eng
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Zusammenfassung:The composition for stimulating an immune response in a subject comprises methyl vinyl ether and maleic anhydride copolymer-based nanoparticles. Said nanoparticles may further contain an allergen or an antigen and/or an immunostimulating agent, which may be contained inside said nanoparticles and/or at least partially coating the surface of said nanoparticles, and optionally a cross-linking agent. The immune response stimulating composition is useful as an adjuvant in immunotherapy and vaccines.