Aminodihydrothiazine derivatives substituted with a cyclic group

This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R2a and R2b...

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Hauptverfasser: MATSUMOTO SAE, KOORIYAMA YUUJI, SUZUKI SHINJI, TADA YUKIO, UENO TATSUHIKO, FUJIKOSHI CHIAKI, TAMURA YUUSUKE, YONEZAWA SHUJI
Format: Patent
Sprache:eng
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Zusammenfassung:This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R3a, R3b, R3c and R3d are each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.; a pharmaceutically acceptable salt or solvate thereof, which is useful for treating diseases induced by production, secretion and/or deposition of amyloid protein.