Pharmaceutical composition and administrations thereof

The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CAESAR, JR. JOHN P, DAS LAURA, FAWAZ MAJED, DOKOU ELENI, GU CHONG-HUI, HURTER PATRICIA NELL, ISRANI MEGHNA JAI, KUZMISSION ANDREW G, KNEZIC DRAGUTIN, WANG HONGREN, JAMZAD SHAHLA, JOHNSTON MEGHAN M
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.