Process for the synthesis of 37-mer peptide pramlintide

Process for the synthesis of 37-mer peptide pramlintide

A process for the production of pramlintide, a 37-mer peptide, is provided. The synthesis provides a high yield synthesis of the peptide in relatively pure form. Further purification can be achieved by preparative HPLC.

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Bibliographische Detailangaben
Hauptverfasser: MOHE NIKHIL UMESH, CHAVRE PRAFUL SHAMRAO, MURALIDHARAN CHANDRAKESAN, SAKSENA DIVYA LAL, DESHMUKH BHARTI PRABHAKARRAO, PAWAR DIGAMBER SHRIPATI, LOBO LESTER JOHN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A process for the production of pramlintide, a 37-mer peptide, is provided. The synthesis provides a high yield synthesis of the peptide in relatively pure form. Further purification can be achieved by preparative HPLC.