Decontamination systems and methods of use thereof

A system for reducing biological and/or chemical contaminants within a feed fluid stream includes in one embodiment at least one recuperator having a cold pass and a hot pass, wherein a contaminated fluid stream is introduced into the cold pass of the recuperator; optionally heating the feed fluid stream using a heater; and introducing the feed fluid stream into a compressor, and compressing the fluid stream to an elevated pressure, resulting in heating of the fluid stream to an elevated temperature, thereby producing a decontaminated fluid stream.