Inhibitors of the hedgehog pathway

The present invention is directed to a compound of Formula I or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Fo...

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Hauptverfasser: MARLOWE CHARLES K, TAKEUCHI CRAIG STACY, BAJJALIEH WILLIAM, KIM BYUNG GYU, WANG YONG, FORSYTH TIMOTHY PATRICK, MANN GRACE, SHI XIAN, LEAHY JAMES W, CHEN JEFF, MAC MORRISON B, HUYNH TAI PHAT, LEWIS GARY L, RIDGWAY BRIAN HUGH, SANGALANG JOAN C, LEE MATTHEW SANGYUP, EPSHTEYN SERGEY, BAHCECI SULEYMAN
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is directed to a compound of Formula I or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula I to treat cancer.