Multidimensional supramolecular structures essentially made of assembled i-motif tetramers

Multidimensional supramolecular structures essentially made of assembled i-motif tetramers

The present invention pertains to a supramolecular structure based on i-motif tetramers of Cm-X-Cn oligonucleotides, wherein m and n are integers comprised between 2 and 9, and X is a linker such as A, T, G, a modified deoxynucleotide or a diol spacer. These supramolecular structures can be dissocia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: POMPON DENIS, LAISNE AUDE, LEROY JEAN-LOUIS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The present invention pertains to a supramolecular structure based on i-motif tetramers of Cm-X-Cn oligonucleotides, wherein m and n are integers comprised between 2 and 9, and X is a linker such as A, T, G, a modified deoxynucleotide or a diol spacer. These supramolecular structures can be dissociated, when necessary, by a mere pH change. The present invention also relates to methods for obtaining such a supramolecular structure.