Deazapurines useful as inhibitors of Janus kinases

The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CAO JINGRONG, LEDEBOER MARK, MARTINEZ-BOTELLA GABRIEL, WANNAMAKER MARION, MALTAIS FRANCOIS, FORSTER CORNELIA, SALITURO FRANCESCO, MARONE VALERIE, FARMER LUC, PIERCE ALBERT, GAO HUAI, DUFFY JOHN, WANG TIANSHENG, MESSERSMITH DAVID
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The compounds are generally represented by structural formula I or pharmaceutically acceptable salts thereof: