Phenyl-heteroaryl derivatives and methods of use thereof

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of co...

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Bibliographische Detailangaben
Hauptverfasser:	BONDLELA MURALIDHAR, SUNDERMANN KURT, ZHU JEFF J, RAO MOHAN, ANDREWS ROBERT C, JONES DAVID, BANNER WILLIAM K, WANG PINGZHEN, COOPER JEREMY T, QABAJA GHASSAN, GOWDA RAJU B, XIE RONGYUAN, GUPTA SUPARNA, GOHIMUKKULA DEVI R, HARI ANITHA
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.