Immune complex-specific antibodies for increased sensitivity in immunoassay array tests

The invention concerns a method for determining antigen-specific antibodies of a particular immunoglobulin class in a sample by means of an immunoassay in an array format in which various binding partners Bnx are bound on different discrete areas on a support where Bnx in each case contain the vario...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LENZ HELMUT, MARKERT-HAHN CHRISTINE, KLAUSE URSULA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention concerns a method for determining antigen-specific antibodies of a particular immunoglobulin class in a sample by means of an immunoassay in an array format in which various binding partners Bnx are bound on different discrete areas on a support where Bnx in each case contain the various antigens that are able to specifically bind to the antibodies to be detected, by incubating the support with the sample and a binding partner B2 which carries a label and subsequently detecting the label on the respective discrete areas wherein B2 specifically binds antibodies of a certain immunoglobulin class that have been bound in an antigen-specific manner.