Method of treating aberrant mucus production in respiratory disease

The present invention relates to modulators of the Neuregulin (NRG) family, particularly NRG1 and more particularly NRG1beta, and most particularly NRG1beta1. The present invention also relates to the use of such modulators to inhibit goblet cell hyperplasia and therefore also relates to the use of...

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Bibliographische Detailangaben
Hauptverfasser: JACKSON ALAN, JONES CAROL ELIZABETH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to modulators of the Neuregulin (NRG) family, particularly NRG1 and more particularly NRG1beta, and most particularly NRG1beta1. The present invention also relates to the use of such modulators to inhibit goblet cell hyperplasia and therefore also relates to the use of such modulators in the treatment or prevention of human diseases and disorders featuring pathological mucus production such as COPD, CF, chronic bronchitis and asthma.