Compartment segregation by pixel characterization using image data clustering

The present invention relates generally to improved methods of defining areas or compartments within which biomarker expression is detected and quantified. In particular, the present invention relates to automated methods for delineating marker-defined compartments objectively with minimal operator...

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Bibliographische Detailangaben
Hauptverfasser: BOURKE BRIAN, CHRISTIANSEN JASON H, GUSTAVSON MARK, REILLY DYLAN M, PINARD ROBERT, TEDESCHI GREGORY R
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates generally to improved methods of defining areas or compartments within which biomarker expression is detected and quantified. In particular, the present invention relates to automated methods for delineating marker-defined compartments objectively with minimal operator intervention or decision making. The method provides for precise definition of tissue, cellular or subcellular compartments particularly in histological tissue sections in which to quantitatively analyzing protein expression.