Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators

Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.

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Bibliographische Detailangaben
Hauptverfasser:	SAVALL BRAD M, CHAI WENYING, SHAH CHANDRAVADAN R, LETAVIC MICHAEL A, LY KIEV S, SAPPEY KATHLEEN C, PIPPEL DANIEL J, STOCKING EMILY M, SWANSON DEVIN M, SOYODE-JOHNSON AKINOLA, RUDOLPH DALE A, SHIREMAN BROCK T
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.