2-aminopyridine and 2-pyridone C-nucleosides

The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonucleotide-based diagnosis and separation throug...

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Hauptverfasser: FROEHLER BRIAN C, MATTEUCCI MARK D, GUTIERREZ ARNOLD J
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonucleotide-based diagnosis and separation through triplex binding.