Intracardiac implant for delivery of alarmins and methods thereof

The invention provides a cardiovascular occluder for treating a cardiovascular abnormality comprising a frame and an alarmin or an alarmin activator bound to the surface of the frame. The invention further provides methods of manufacturing the cardiovascular occluder and methods of treating cardiova...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAFFERATA ROBERT L, KLADAKIS STEPHANIE M
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a cardiovascular occluder for treating a cardiovascular abnormality comprising a frame and an alarmin or an alarmin activator bound to the surface of the frame. The invention further provides methods of manufacturing the cardiovascular occluder and methods of treating cardiovascular abnormalities by delivering the cardiovascular occluder.