System for the noninvasive determination of tracer concentration in blood

The invention relates to a general composite compartmental model and a compartmental analysis procedure to extract non-invasively the concentration (Cp) of the imaging agent in plasma (301), in metabolites (304, 504) and in blood elements (303) (like red cells, platelets, plasma protein etc.) from t...

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Bibliographische Detailangaben
Hauptverfasser:	SPIES LOTHAR, PAULUS TIMO, PELIGRAD DRAGOS-NICOLAE
Format:	Patent
Sprache:	eng
Schlagworte:	CALCULATING COMPUTING COUNTING DIAGNOSIS ELECTRIC DIGITAL DATA PROCESSING HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA HUMAN NECESSITIES HYGIENE IDENTIFICATION INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEDICAL OR VETERINARY SCIENCE PHYSICS SURGERY
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Beschreibung
Zusammenfassung:	The invention relates to a general composite compartmental model and a compartmental analysis procedure to extract non-invasively the concentration (Cp) of the imaging agent in plasma (301), in metabolites (304, 504) and in blood elements (303) (like red cells, platelets, plasma protein etc.) from time signal curves measured within a reference tissue region (200). This is made possible by deploying an injection function (SINJ(t)) as input which models the amount of imaging agent administered to the patient as a function of time. The invention allows the presentation of the plasma input function to the medical practitioner without the need for invasively drawing blood samples.