Systems and methods for performing design of experiments

A method of automatically designing a plurality of experiments for analyzing at least one data set from a process to determine a relationship of a plurality of process factors of interest to a process output of interest. The method uses a computer to elicit input from a user to determine at least one characteristic of the data set including a quantity of the plurality of factors and whether one or more of the plurality of factors has greater than two levels, selects a design from a plurality of experiment designs based on established conventions for each of the plurality of experiment designs, the design applicable to the elicited at least one characteristic of the data set, and provides a design of experiments including a standard order of the experiments and a run order of the experiments, the design of experiments indicating the combinations of factors and levels for each experiment.