Substituted arylamine compounds and methods of treatment
The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity...
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| creator | SHARADENDU ANURAG ORBACH PINI CHERUKU SRINIVASA RAO WU LAURENCE MARANTZ YAEL LOBERA MERCEDES SENDEROWITZ HANOCH DHANOA DALE S FICHMAN MERAV SHACHAM SHARON SAHA ASHIS MELENDEZ ROSA BECKER OREN |
| description | The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type II diabetes; and psychological disorders such as schizophrenia, are disclosed. |
| format | Patent |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Substituted arylamine compounds and methods of treatment |
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