Substituted arylamine compounds and methods of treatment

The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity...

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Bibliographische Detailangaben
Hauptverfasser:	SHARADENDU ANURAG, ORBACH PINI, CHERUKU SRINIVASA RAO, WU LAURENCE, MARANTZ YAEL, LOBERA MERCEDES, SENDEROWITZ HANOCH, DHANOA DALE S, FICHMAN MERAV, SHACHAM SHARON, SAHA ASHIS, MELENDEZ ROSA, BECKER OREN
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type II diabetes; and psychological disorders such as schizophrenia, are disclosed.