Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels

The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorder...

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Hauptverfasser: PONTILLO JOSEPH, GROOTENHUIS PETER DIEDERIK JAN, HADIDA-RUAH SARA SABINA, MCCARTNEY JASON, HILGRAF NICOLE, KALLEL EDWARD ADAM, ANDERSON COREY, NUMA MEHDI, BEAR BRIAN RICHARD, JOHNSON, JR. JAMES PHILIP, MILLER MARK THOMAS, ARUMUGAM VIJAYALAKSMI, FRIEMAN BRYAN A
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creator PONTILLO JOSEPH
GROOTENHUIS PETER DIEDERIK JAN
HADIDA-RUAH SARA SABINA
MCCARTNEY JASON
HILGRAF NICOLE
KALLEL EDWARD ADAM
ANDERSON COREY
NUMA MEHDI
BEAR BRIAN RICHARD
JOHNSON, JR. JAMES PHILIP
MILLER MARK THOMAS
ARUMUGAM VIJAYALAKSMI
FRIEMAN BRYAN A
description The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
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