Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels

The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorder...

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Hauptverfasser: PONTILLO JOSEPH, GROOTENHUIS PETER DIEDERIK JAN, HADIDA-RUAH SARA SABINA, MCCARTNEY JASON, HILGRAF NICOLE, KALLEL EDWARD ADAM, ANDERSON COREY, NUMA MEHDI, BEAR BRIAN RICHARD, JOHNSON, JR. JAMES PHILIP, MILLER MARK THOMAS, ARUMUGAM VIJAYALAKSMI, FRIEMAN BRYAN A
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.