Crystalline form I of 3,4'5-trihydroxy-stilbene-3-beta-D glucoside

The present invention relates to a novel crystalline form of a Compound 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside (polydatin) and a method of preparation and use thereof, and to a pharmaceutical composition containing crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YAO GUANGHUI, WANG CUNFANG, ZHU DAN, LI YONG, LI JING, FENG HANLIN, ZHAO JINHUA, ZHANG LIJUAN, MAN YU, KANG HUI, ZENG WEIZHEN, CHEN HONG, YU LIN, YIN MILAI, HUANG CHUANGUI
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to a novel crystalline form of a Compound 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside (polydatin) and a method of preparation and use thereof, and to a pharmaceutical composition containing crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside. Crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside of the present invention has a stable crystalline morphology, a definite melting point and a good chemical stability. Such a novel form of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside possesses the properties required for the preparation of solid formulations and is easily tabletable and readily formable when formulated, which allows for substantial decrease in raw materials costs, more facile operations in production and easier control over quality in industrial drug production, and moreover, better convenience in storage.