Crystalline form I of 3,4'5-trihydroxy-stilbene-3-beta-D glucoside
The present invention relates to a novel crystalline form of a Compound 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside (polydatin) and a method of preparation and use thereof, and to a pharmaceutical composition containing crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside....
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | The present invention relates to a novel crystalline form of a Compound 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside (polydatin) and a method of preparation and use thereof, and to a pharmaceutical composition containing crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside. Crystalline form I of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside of the present invention has a stable crystalline morphology, a definite melting point and a good chemical stability. Such a novel form of 3,4',5-trihydroxy-stilbene-3-beta-D-glucoside possesses the properties required for the preparation of solid formulations and is easily tabletable and readily formable when formulated, which allows for substantial decrease in raw materials costs, more facile operations in production and easier control over quality in industrial drug production, and moreover, better convenience in storage. |
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