Isolation of a dual COX-2 and 5-lipoxygenase inhibitor from acacia

The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also include...

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Hauptverfasser: WAITE SCOTT, NICHOLS TIMOTHY C, RHODEN ERIC E, JIA QI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides compositions and methods for alleviating inflammatory-associated diseases and conditions. These methods include administering individual and/or a mixture of multiple flavans isolated from a single or multiple Acacia genus of plants. The present disclosure also includes methods for isolating and purifying from an Acacia genus of plants a composition of flavans having dual specificity for cyclooxygenase (COX-2) and 5-lipoxygenase (5-LO) enzymes.