Process for the preparation of pyrazinone thrombin inhibitor and its intermediates

Process for the preparation of pyrazinone thrombin inhibitor and its intermediates

Improved process for the preparation of 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide of formula (I) and its intermediates is provided.

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Bibliographische Detailangaben
Hauptverfasser: SAHU NILAM, REDDY REGURI BUCHI, RAO JAWAJI KARUNAKARA, REDDY GADE BRAHMA, SAMPATHKUMAR UPPARAPALLI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Improved process for the preparation of 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2-pyridyl)ethylamino)-6-chloropyrazin-2-one-1-acetamide of formula (I) and its intermediates is provided.