Method of production of 9-cis-retinoic acid

Improved method of production of 9-(Z)-retinoic acid, in which a) a beta-formyl-crotonic acid C1-C10 alkyl or phenyl ester is reacted with an isolated 9-(Z)-C15-triarylphosphonium salt by the Wittig reaction in the presence of a base to the corresponding 9-(Z)-retinoic acid ester; which b) is then s...

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Bibliographische Detailangaben
Hauptverfasser: KNOPP MONIKA, KUEBEL ERWIN, STANEK MICHAEL, ESSL STEFAN
Format: Patent
Sprache:eng
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