Acetylene derivatives having MGluR 5 antagonistic activity

The invention provides compounds of formula I wherein n, A, R, R', R'', RO, X and Y are as defined in the description, and their preparation. The compounds of formula I are useful as pharmaceuticals.

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Bibliographische Detailangaben
Hauptverfasser:	AUBERSON YVES, OFNER SILVIO, ZIMMERMAN KASPAR, HART TERANCE W, GASPARINI FABRIZIO
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides compounds of formula I wherein n, A, R, R', R'', RO, X and Y are as defined in the description, and their preparation. The compounds of formula I are useful as pharmaceuticals.