Crystalline solid and amorphous forms of (-)-halofenate and methods related thereto

The present invention provides crystalline solid and amorphous forms of (-)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal,...

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Bibliographische Detailangaben
Hauptverfasser: DAUGS EDWARD D, LOUKS DAVID H, HANKO JASON A, HAGEN ERIC J
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides crystalline solid and amorphous forms of (-)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal, particularly those diseases related to Type 2 diabetes and hyperlipidemia. The invention also relates to a method for preventing or treating Type 2 diabetes and hyperlipidemia in a mammal comprising the step of administering a therapeutically effective amount of crystalline solid and amorphous forms of (-)-halofenate.