VHNAR anti-cytokine domains

The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach,...

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Hauptverfasser: PANIAGUA-SOLIS JORGE F, CAMACHO-VILLEGAS TANYA A, OLGUIN-JIMENEZ ARACELI, LICEA-NAVARRO ALEXEI F, MATA-GONZALEZ MARIA TERESA, GARCIA-UBBELOHDE WALTER J, SANCHEZ-CASTREJON EDNA
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach, bind, and neutralize the activity of one antigenic molecule localized in an immunoprivileged organs, are also described.