Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy

Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy

The invention relates to special nucleosides, for example, a nucleoside of the formula I, wherein R1-R5 are as described herein, and also to drugs which contain these nucleosides. Furthermore, the invention relates to the use of such nucleosides in a method for suppressing or reducing the formation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HEINRICH JORGRISTIAN, TEUBNER JANEK, DIEKS HENRIK, FAHRIG RUDOLF, ROLFS ANDREAS, LOHMANN DIETER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The invention relates to special nucleosides, for example, a nucleoside of the formula I, wherein R1-R5 are as described herein, and also to drugs which contain these nucleosides. Furthermore, the invention relates to the use of such nucleosides in a method for suppressing or reducing the formation of resistance in the case of cytotstatic treatment of a cancer patient.