Selective catalytic reduction (SCR) catalyst depletion control systems and methods

A dosing control system for a vehicle includes an adaption triggering module, a dosing management module, and an adaption ending module. The adaptation triggering module triggers performance of an adaptation event when a first amount of nitrogen oxides (NOx) measured by a first NOx sensor located downstream of a selective catalytic reduction (SCR) catalyst is greater than a predicted value of the first amount of NOx. The dosing management module disables dosing agent injection during the adaptation event. The adaptation ending module selectively delays ending the adaptation event after a predetermined number of phases of the adaption event have been completed based on a comparison of the first amount of NOx with a second amount of NOx measured by a second NOx sensor located upstream of the SCR catalyst.