Tamper resistant lipid-based oral dosage form for sympathomimetic amines

A tamper resistant drug delivery system made of at least one lipid, at least one gelling agent and at least one sympathomimetic amine, such as for example pseudoephedrine, wherein the system gels in the presence of water or a solution containing water and ethanol, wherein the sympathomimetic amine r...

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Bibliographische Detailangaben
Hauptverfasser: BAUSCH JAMES M, LEWIS LINDA L, KERSHMAN ALVIN, SHEAR JEFF
Format: Patent
Sprache:eng
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Zusammenfassung:A tamper resistant drug delivery system made of at least one lipid, at least one gelling agent and at least one sympathomimetic amine, such as for example pseudoephedrine, wherein the system gels in the presence of water or a solution containing water and ethanol, wherein the sympathomimetic amine releases into the digestive system when ingested, and wherein the weight ratio of gelling agent to lipid is less than 1:1.4.