Systems and methods for data-selection-specific data deduplication

A computer-implemented method for data-selection-specific data deduplication associated with a single-instance-storage computing subsystem may comprise: 1) detecting a request to store a data selection to the single-instance-storage computing subsystem, 2) identifying a data-selection-specific fingerprint set associated with the data selection and stored on a storage device, and 3) utilizing the data-selection-specific fingerprint set associated with the data selection for data deduplication associated with the request to store the data selection to the single-instance-storage computing subsystem. Other exemplary data deduplication methods, as well as corresponding exemplary systems and computer-readable media, are also disclosed.