5-lipoxygenase-activating protein (FLAP) inhibitors
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory,...
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| creator | HUTCHINSON JOHN H PRASIT PETPIBOON PEPPI STOCK NICHOLAS SIMON EVANS JILLIAN F HADDACH MUSTAPHA STEARNS BRIAN ANDREW MORAN MARK ZUNIC JASMINE ELEANOR ROPPE JEFFREY ROGER LI YIWEI ARRUDA JEANNIE M |
| description | Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 5-lipoxygenase-activating protein (FLAP) inhibitors |
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