Preparation of poly(ethylene oxide)-coated nanoparticles of maghemite

The invention relates to a material consisting of an aqueous dispersion of PEG-coated nanoparticles of maghemite. The process for preparing said material consists in polymerizing ethylene oxide in the presence of nanoparticles of maghemite in an aqueous dispersion. The polymerization is initiated us...

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Bibliographische Detailangaben
Hauptverfasser:	FLESCH CHRISTOPHE, DUMAS PHILIPPE, DELAITE CHRISTELLE
Format:	Patent
Sprache:	eng
Schlagworte:	BASIC ELECTRIC ELEMENTS ELECTRICITY HUMAN NECESSITIES HYGIENE INDUCTANCES MAGNETS MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEDICAL OR VETERINARY SCIENCE NANOTECHNOLOGY PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES TRANSFORMERS TRANSPORTING
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Beschreibung
Zusammenfassung:	The invention relates to a material consisting of an aqueous dispersion of PEG-coated nanoparticles of maghemite. The process for preparing said material consists in polymerizing ethylene oxide in the presence of nanoparticles of maghemite in an aqueous dispersion. The polymerization is initiated using reactive groups which are capable of initiating the polymerization of ethylene oxide without the addition of a catalyst, and which are attached to the nanoparticles of maghemite by means of a coupling agent comprising an alkoxysilyl group and one or more of said reactive groups. Applications: contrast agent for MRI.