Process for the synthesis of 9α-hydroxy-steroids

The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)-wherein the meaning of -A-A′- is -CH2-CH2- or -CH CH- group-by the bioconversion of compounds of the general formula (II) (II) wherein the meaning of -A-A′- is -CH2-CH2- or -...

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Bibliographische Detailangaben
Hauptverfasser:	OLASZ KATALIN, TEGDES ANIKO, KOENCZOEL KALMAN, HANTOS GABOR, BALOGH GABOR, GANCSOS VALERIA, ERDELYI SANDOR
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)-wherein the meaning of -A-A′- is -CH2-CH2- or -CH CH- group-by the bioconversion of compounds of the general formula (II) (II) wherein the meaning of -A-A′- is -CH2-CH2- or -CH CH- group-by using Nocardia farcinica bacterium strain, deposition number of which is NCAIM (P)-B 001342, as hydroxylating microorganism in the bioconversion.