Macrocyclic compound

The present invention provides a novel class of compounds that have the activity of inhibiting HSP90 enzyme and are useful as anti-cancer agents or such, and compounds that are useful as synthetic intermediates thereof. Specifically, the present invention provides compounds represented by the follow...

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Bibliographische Detailangaben
Hauptverfasser:	KAWASAKI KEN-ICHI, ONO NAOMI, SAITOH RYOICHI, KOHCHI MASAMI, HAYASE TADAKATSU, SHIMMA NOBUO, HASEGAWA KIYOSHI, SUDA ATSUSHI, KOMIYAMA SUSUMU, KOYANO HIROSHI, HADA KIHITO, TSUKUDA TAKUO, YAMAZAKI TOSHIKAZU
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a novel class of compounds that have the activity of inhibiting HSP90 enzyme and are useful as anti-cancer agents or such, and compounds that are useful as synthetic intermediates thereof. Specifically, the present invention provides compounds represented by the following formula (1), and pharmaceutically acceptable salts thereof: wherein X, R1, R2, R3, R4, R5, R6, R7, L1, L2, and L3 are as defined in the specification.