Pyrimidine amide compounds as PGDS inhibitors

Pyrimidine amide compounds as PGDS inhibitors

This invention is directed to a compound of formula (I): wherein R1, R2, R3 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LU JINQI, ALDOUS SUZANNE C, MA LIANG, JIANG JOHN ZIQI, THURAIRATNAM SUKANTHINI, MU LAN, MUNSON HARRY RANDALL, VANDEUSEN CHRISTOPHER LOREN, SABOL JEFFREY STEPHEN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This invention is directed to a compound of formula (I): wherein R1, R2, R3 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).