Process for the preparation of novel pyridopyrazines as mTOR kinase inhibitors

Process for the preparation of novel pyridopyrazines as mTOR kinase inhibitors

There is provided a process for the preparation of a compound of Formula 1, the use of said process in the preparation of a compound of Formula 5 or a phosphate, sulphate, hydrogensulphate, malate, citrate, tartrate or fumarate salt thereof, and the use of the fumarate salt in a composition for use...

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Bibliographische Detailangaben
Hauptverfasser: DOBSON BENJAMIN CHARLES, BLADE HELEN, CHURCHILL GWYDION HUW, RAW STEVEN ANTHONY, CURRIE ANGELA CHARLOTTE, KENWORTHY MARTIN NEAL, POWELL LYN, HYNES PETER SAMUEL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:There is provided a process for the preparation of a compound of Formula 1, the use of said process in the preparation of a compound of Formula 5 or a phosphate, sulphate, hydrogensulphate, malate, citrate, tartrate or fumarate salt thereof, and the use of the fumarate salt in a composition for use in therapy.