Process for the preparation of sevelamer hydrochloride and formulation thereof

Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous...

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Hauptverfasser: CHOUDHARY VARSHA SHASHANK, BHIDE YOGESH SHARAD, PATIL SAMADHAN DAULAT, MONDKAR HARISH KASHINATH, HEGDE DEEPAK ANANT, SATHE DHANANJAY GOVIND, THOOVARA SASIKUMAR MOHAN, TARUR VENKATASUBRAMANIAN RADHAKRISHNAN
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed herein is an improved process for preparation of Sevelamer hydrochloride having phosphate binding capacity of 4.7 to 6.4 mmol/g. Further, the invention discloses Sevelamer hydrochloride compositions and a novel process for preparation of said compositions comprising high shear non-aqueous granulation.