Substituted imidazoles as bombesin receptor subtype-3 modulators

Substituted imidazoles as bombesin receptor subtype-3 modulators

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BR...

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Hauptverfasser: GUO CHENG, GUZZO PETER R, JIAN TIANYING, LIN LINUS S, YET LARRY, LIU JIAN, SEBHAT IYASSU K, SARGENT BRUCE J, FRANKLIN CHRISTOPHER L, RUENZ MEGAN, GOODMAN ALLAN, DOBBELAAR PETER H, HE SHUWEN, HADDEN MARK, NARGUND RAVI P, HENDERSON ALAN J
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.