Preparation of pregabalin and related compounds

Materials and methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.

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Bibliographische Detailangaben
Hauptverfasser: MARTINEZ CARLOS ALBERTO, HU SHANGHUI, DUMOND YVES, TAO JUNHUA, KELLEHER PATRICK, TULLY WILLIAM EUGENE
Format: Patent
Sprache:eng
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Zusammenfassung:Materials and methods for preparing (S)-(+)-3-aminomethyl-5-methyl-hexanoic acid and structurally related compounds via enzymatic kinetic resolution are disclosed.