Network devices with multiple direct memory access channels and methods thereof

A method, computer readable medium, and a system for communicating with networked clients and servers through a network device includes establishing a plurality of direct memory access (DMA) channels across a host system bus over which a plurality of executing applications each having a respective application driver communicate with a network through a network device configured to receive and transmit network data packets. At a first port in the network device, a first network data packet destined for an executing application is received. A first DMA channel over which to transmit the first network data packet towards the destined executing application is identified, and the first network data packet is transmitted to the destination executing application over the designated DMA channel mapping to the first port.