9-aminocarbonylsubstituted derivatives of glycylcyclines

9-aminocarbonylsubstituted derivatives of glycylcyclines

This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according to Formula (II): where Q, R4, R5, R6 and R10 and A are defined in the specific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VERA MATTHEW DOUGLAS, SHIM JAECHUL, HOW DAVID BRIAN, SUM PHAIK-ENG, MANSOUR TAREK SUHAYL, HOPPER DARRIN WILLIAM, SABATINI JOSHUA JAMES
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial agents. Compounds according to Formula (II): where Q, R4, R5, R6 and R10 and A are defined in the specification are useful as chemical intermediates.