Assay method for group transfer reactions

An isolated antibody produced against a donor product of an enzymatically catalyzed group transfer reaction is disclosed. In one aspect, the antibody has the ability to preferentially recognize the donor-product guanosine diphosphate (GDP), in the presence of the donor molecule guanosine triphosphat...

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Bibliographische Detailangaben
Hauptverfasser: KLEMAN-LEYER KAREN, LOWERY ROBERT, STAEBEN MATT, WESTERMEYER THANE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An isolated antibody produced against a donor product of an enzymatically catalyzed group transfer reaction is disclosed. In one aspect, the antibody has the ability to preferentially recognize the donor-product guanosine diphosphate (GDP), in the presence of the donor molecule guanosine triphosphate (GTP). Immunuoassays using compositions including such antibodies and kits for performing the immunoassays are also disclosed.