Process for preparing benzimidazole compounds

Process for preparing benzimidazole compounds

Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X1, X2, X5, R2 and R10 are as defined herein. Compounds of Formula Ia-1 and their synthetic intermediates can be us...

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Bibliographische Detailangaben
Hauptverfasser: PEETERS KOEN, EVANS MATTHEW CHARLES, LILLEY TIMOTHY JOHN, LEONARD JOHN, PISCOPIO ANTHONY D, FORD JAMES GAIR, DEMATTEI JOHN, SHAKYA SAGAR, HACHE BRUNO P, POINTON SIMON MARK
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X1, X2, X5, R2 and R10 are as defined herein. Compounds of Formula Ia-1 and their synthetic intermediates can be used to prepare heterocyclic derivatives such as benzimidazole derivatives.