Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Heteroaryl compounds, compositions thereof, and methods of treatment therewith

Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions,...

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Bibliographische Detailangaben
Hauptverfasser: CLAREEN STEVEN SPENCER, MORTENSEN DEBORAH SUE, PARNES JASON SIMON, SAPIENZA JOHN JOSEPH, RIGGS JENNIFER R, PAPA PATRICK WILLIAM, MCKENNA JEFFREY MARK, DELGADO MEDEROS MARIA MERCEDES, SCHWARZ KIMBERLY LYN, ALBERS RONALD J, HEGDE SAYEE GAJANAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.