Inhalable epinephrine

The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described herein comprise the bioactive agen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHILDS MARIKO, HRKACH JEFFREY S, LI WEN-I, LIPP MICHAEL M, BATYCKY RICHARD P, CAPONETTI GIOVANNI, FU KAREN, SUMMA JASON, EHRICH ELLIOT, PAN MEI-LING
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described herein comprise the bioactive agent epinephrine, or a salt thereof, as a therapeutic agent. The particles are preferably formed by spray drying. Preferably, the particles and the respirable compositions are substantially dry and are substantially free of propellents. In a preferred embodiment, the particles have aerodynamic characteristics that permit targeted delivery of epinephrine to the site(s) of action.