N-aroyl cyclic amine derivatives as orexin receptor antagonists

N-aroyl cyclic amine derivatives as orexin receptor antagonists

Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.

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Bibliographische Detailangaben
Hauptverfasser: NOVELLI RICCARDO, PORTER RODERICK ALAN, CHAN WAI NGOR, PILLEUX JEAN-PIERRE, JOHNSON CHRISTOPHER NORBERT, STEAD RACHEL ELIZABETH ANNE, JOHNS AMANDA, STEMP GEOFFREY, BRANCH CLIVE LESLIE, NASH DAVID JOHN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.