Fermentation with cyclic pulse-pause feeding

A process for the production of a valuable compound, comprising the steps of a) fermentation of a filamentous bacterial or fungal strain (e.g. a Streptomyces strain or an Aspergillus strain) in a fermentation medium wherein a carbohydrate during fermentation is added in a cyclic pulse dosing/pause w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WENGER KEVIN S, STOCKS STUART MICHAEL, MARTEN MARK R, BHARGAVA SWAPNIL, CAICEDO MARIA ANTONIETA
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:A process for the production of a valuable compound, comprising the steps of a) fermentation of a filamentous bacterial or fungal strain (e.g. a Streptomyces strain or an Aspergillus strain) in a fermentation medium wherein a carbohydrate during fermentation is added in a cyclic pulse dosing/pause way, wherein the pulse dosing time is shorter than the pause time and b) recovery of the valuable compound from the fermentation broth.