Glucagon receptor antagonists, preparation and therapeutic uses

The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHU GUOXIN, CONNER SCOTT EUGENE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.